Medicine&Drugs Whitening Skin for Vitiligo Use Monobenzone

Model NO.: NH932d520


Usage Mode: For external use


State: Solid


Type: Biological Products


Name: Monobenzone Cream(for Vitiligo)


MOQ: 1 Box


Quality Standard: GMP/Who GMP/Euro GMP


Delivery Time: 7 Days


Trademark: guyenne


Origin: France




Application: Internal Medicine


Suitable for: Elderly, Children, Adult


Shape: Powder


Pharmaceutical Technology: Chemical Synthesis


Brand&Origin: Guyenne, France


Sample: Acceptable


Port: Guangzhou


Shelf Life: 36 Months


Specification: 20g, 27g


HS Code: 29095090


MONOBENZONE CREAM





DESCRIPTION

Product Name:	Monobenzone	Appearance :	White crystline powder
CAS:	103-16-2	Molecular formula:	C20H20O3
Molecular weight :	308.371	Supplier name:	KINGSCI
Synonyms:	(Benzyloxy)phenol; p-Hydroxyphenyl benzyl ether; 4-(Phenylmethoxy)phenol; Agerite alba; Benoquin; Benzoquin; Benzyl hydroquinone; Depigman; Hydroquinone benzyl ether; Monobenzone; Monobenzyl hydroquinone; PBP; Pigmex; 4-benzyloxy phenol (Monobenzone); 4-benzyloxy phenol; 4-(benzyloxy)phenol; 4-Benzyloxyphenol; PHENOL,4-(PHENYLMETHOXY)-
Specification	99.5%

(1)Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.



(2)Monobenzone is a compound used as a topical drug for medical depigmentation. The Topical Application of monobenzone in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes thus, bringing about permanent dipigmentation in vitiligo patients.



(3)Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone powder can be compounded to make a depigmenting cream. It is used to whiten patchy skin and create and even skin tone that is pale and smooth.



(4)Monobenzone USP, is a strong depigmentation agent, used to treat the patients suffering from vitiligo.

(5)Monobenzone 20% ointment is used specifically for vitiligo.



FUNCTION

1.Monobenzone is a compound used as a topical drug for medical depigmentation.

2.The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes.

3.The same action is thought to be responsible for the depigmenting effect of the drug in humans.

4.Monobenzone may cause destruction of melanocytes and permanent depigmentation.

5.The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo.

6.The epidermis is normal except for the absence of identifiable melanocytes.



APPLICATION

Monobenzone is used to treat the loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo.

Do not use this medication for other skin color conditions (e.g., freckling, age spots, etc.)



Production Procedure:



Raw Materials----Degreasing and Decalcification-----Enzymolysis----Decolorizing and Deflavour----- Premilinary Millipore Filtration----Refined Filtration---- Concentration------Spray Drying------Prilling-------Package in GMP workshop



SPECIFICATION

ANALYSIS	SPECIFICATION	RUSULT
Assay (HPLC)	Min 99.5%	99.821%
Characters/appearance	Off White powder	Complies
Melting point	117-122	Complies
Water	0.05% Max	Complies
Package & Storage	Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Shelf Life	2 years if sealed and avoid direct sun light.
Conclusion	Conforming to standards of European pharmacopoeia 4

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Product Categories : Biologicals & Vaccines