30mg Gastro-Resistant Lansoprazole for Injection

Model NO.: DAWAGRL0001 Usage Mode: For external use State: Solid Type: Biological Products MOQ: 1 Vials/Box Storage: Below 30 Degree Trademark: GUYENNE Origin: France Application: Internal Medicine Suitable for: Elderly, Children, Adult Shape: Powder Pharmaceutical Technology: Chemical Synthesis OEM: Acceptable Administration Route: I.V Specification: 30mg HS Code: 3004101300 30mg Gastro-Resistant Lansoprazole For Injection
 

Specification	30mg
Packege	10vials/tray/box

Lansoprazole is a proton-pump inhibitor (PPI) which inhibits the stomach's production of gastric acids. It is manufactured by a number of companies worldwide under several brand names. In the United States, it was first approved by the Food and Drug Administration (FDA) in 1995. Prevacid patent protection expired on November 10, 2009.Since 2009, lansoprazole has been available over the counter (OTC) in the U.S. in a 15-mg dose marketed by Novartis as Prevacid 24HR.
Lansoprazole is a proton-pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPIs available. It is a racemic 1:1 mixture of the enantiomers dexlansoprazole (Dexilant, formerly named Kapidex) and levolansoprazole. Dexlansoprazole is an enantiomerically pure active ingredient of a commercial drug as a result of the enantiomeric shift.
Lansoprazole's plasma elimination half-life (1.5 h) is not proportional to the duration of the drug's effects to the person (i.e. gastric acid suppression). and the effects of the drug last for over 24 hours after it has been used for a day or more. Lansoprazole, 30-mg administered nasogastrically, effectively controls intragastric pH and is an alternative to intravenous pantoprazole in patients who are unable to swallow solid-dose formulations.

Indications

Lansoprazole is indicated for treatment of:
Ulcers of the stomach and duodenum, and NSAID-induced ulcers
Helicobacter pylori infection, alongside Antibiotics (adjunctive treatment), treatment to kill H. pylori causing ulcers or other problems involves using two other drugs besides lansoprazole known as "triple therapy", and involves taking twice daily for 10 or 14 days lansoprazole 30-mg
Gastroesophageal reflux disease
Zollinger-Ellison syndrome

Drug interactions

Lansoprazole interacts with several other drugs, either due to its own nature or as a PPI.
 
Increases plasma concentrations of cilostazol (risk of toxicity)
Lansoprazole possibly interacts with, amongst other drugs:
sucralfate
 
bisacodyl
clopidogrel
delavirdine
fluvoxamine
iron salts
 
aminophylline and theophylline
astemizole

Side effects

Side effects of PPIs in general and lansoprazole in particular may include:
Common: diarrhea, abdominal pain
Infrequent: dry mouth, insomnia, drowsiness, blurred vision, rash, pruritus
Rarely and very rarely: taste disturbance, liver dysfunction, peripheral oedema, hypersensitivity reactions (including bronchospasm, urinary, angioedema, anaphylaxis), photosensitivity, fever, sweating, depression, interstitial nephritis, blood disorders (including leukopenia, leukocytosis, pancytopenia, thrombocytopenia), arthralgia, myalgia, skin reactions including (erythroderma[17] Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous eruption)
PPIs may be associated with a greater risk of hip fractures and Clostridium difficile-associated diarrhea

Availability

The lansoprazole molecule is off-patent and so generic drugs are available under many brand names in many countries; there are patents covering some formulations in effect as of 2015.

 

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