High Quality Drug-resistant Mycobacterium Tuberculosis, Inhibition of Tubercle Bacillus, Cell Wall Peptidoglycan Suppliers in China

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Peptide broad-spectrum antibiotics D-cycloserine

Peptide broad-spectrum antibiotics D-cycloserine

    Payment Type: L/C,T/T,D/P,Paypal
    Terms of Trade: FOB,CFR,CIF,FCA,CPT
    Delivery Time: 5 Days
    Transportation: Ocean,Land
    Place of Origin: CHINA
    Port: QINGDAO

Product Description

[density]: 1.3±0.1 g/cm3
[ Boiling point ]: 267oC
[melting point]: 147oC
[ Molecular formula ]: C3H6N2O2
[Molecular Weight]: 102.092
[Exact quality ]: 102.042931
[ PSA ]: 64.35000

[ LogP ]: -1.84

[CAS No.]:68-41-7

[ Appearance traits ]: White to off-white powder
[refractive index]: 1.475
[ Storage conditions ]:

This product should be sealed in a cool dry place away from light.

D-cycloserine is a broad-spectrum antibiotic of the polypeptide produced by Streptomyces lavendulae and S. orchidaces or chemically synthesized. It is white crystal, strong hygroscopicity, soluble in water, soluble in lower alcohol, acetone and dioxane, insoluble in chloroform and petroleum ether; stable in alkaline solution, in acidic and neutral solution Decompose quickly. Cycloserine has a broad antibacterial spectrum. In addition to Mycobacterium tuberculosis, it also inhibits most Gram-positive and negative bacteria, Rickettsia and certain protozoa. For streptomycin, zirconia, and amino-sodium M. tuberculosis resistant to acid, isoniazid, pyrazinamide, etc. also has a role. Cycloserine and isoniazid have a mild synergistic effect on Mycobacterium tuberculosis H37RV, and neither synergistic nor antagonism with streptomycin. This product is a bacteriostatic agent, increasing the dose or prolonging the time of action with bacteria, and does not cause bactericidal action.

The mechanism of the antibacterial action of D-cycloserine is to inhibit the biosynthesis of cell wall peptidoglycan, which is a structural analog of D-alanine, which can competitively inhibit the synthesis of peptidoglycan with D-alanine. Two important enzymes - alanine racemase and D-alanyl-D-alanine synthetase. Its ability to resist Mycobacterium tuberculosis is weak, only 1/10 to 1/20 of streptomycin. The advantage is that it is effective against the resistant strain of the bacteria, and it is not easy to develop resistance to it. This product can be combined with other anti-tuberculosis drugs to treat tuberculosis caused by drug-resistant M. tuberculosis.


Shandong Chenyi Environmental Protection Technology Co.,Ltd

 

Shandong Chen Yi environmental protection technology Co., Ltd is a professional chemical products, pharmaceutical intermediates, pharmaceutical raw materials research and development, production and import and export trade enterprises, enterprise leaders have six years of experience in the chemical industry, R & D engineers in large pharmaceutical enterprises for 10 years. The company has cooperated with Shanghai Weiju Industrial Co., Ltd., Qilu University of Technology, Yanggu Liaoyuan Chemical Co., Ltd. and Shandong Confucius Pharmaceutical Co., Ltd. to establish the enterprise's R&D, production and sales system. The company's long-term stable supply of products include more than 30 categories of organic intermediates, pharmaceutical raw materials, additives, plant extracts, catalyst promoters, organic raw materials, dyes, pigments, flavors and fragrances, mainly including maltol, ribonucleic acid, amino acids, Anti-Cancer Drug intermediates, anti-epileptic drug intermediates, API and some Pharmaceutical accessories, and more than 200 kinds of products. Since its inception, adhering to the "integrity, pragmatic, efficient and innovative" spirit of enterprise, integrity management, law-abiding operation, with the most competitive price, to provide you with higher quality products.

We look forward to establishing good cooperation with you.

We supply different kinds of products. High quality and favorable price. We're pleased to get your Inquiry and we will reply you as soon as possible. We stick to the principle of " Quality first, service first, continuous improvement and innovation to meet the customers" For the management and " Zero defect, zero complaints" As the quality objective.




Company Info

  • Company Name: Shandong Chenyi Environmental Protection Technology Co.,Ltd
  • Representative: LIU YA DONG
  • Product/Service: Pharmaceutical Intermediate , API , Food Additive , Maltol , Organic Raw Material , Organic Intermediate
  • Capital (Million US $): 800,000
  • Year Established: 2017
  • Total Annual Sales Volume (Million US $): US$5 Million - US$10 Million
  • Export Percentage: 91% - 100%
  • Total Annual Purchase Volume (Million US $): US$5 Million - US$10 Million
  • No. of Production Lines: 8
  • No. of R&D Staff: 11 -20 People
  • No. of QC Staff: 5 -10 People
  • OEM Services Provided: yes
  • Factory Size (Sq.meters): 1,000-3,000 square meters
  • Factory Location: Yanggu County, Liaocheng City, Shandong Province
  • Contact Person: Mr. Jerry
  • Tel: 86-0531-18560179988
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